Immunological targeting of cytomegalovirus for glioblastoma therapy

نویسندگان

  • Smita K Nair
  • John H Sampson
  • Duane A Mitchell
چکیده

Human cytomegalovirus (CMV) is purportedly present in glioblastoma (GBM) while absent from the normal brain, making CMV antigens potentially ideal immunological anti-GBM targets. We recently demonstrated that patient-derived CMV pp65-specific T cells are capable of recognizing and killing autologous GBM tumor cells. This data supports CMV antigen-directed immunotherapies against GBM.

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2014